Dr. Edward Cary, empowered by Karl Hoblitzelle and other civic leaders, establishes Southwestern Medical College, the 68th medical school in the United States.


Southwestern Medical College becomes part of The University of Texas System.


Dr. Donald Seldin becomes Chairman of the Department of Internal Medicine, a position he would hold for the next 36 years.


UT Southwestern doctors and Parkland Memorial Hospital staff respond when President John F. Kennedy and Texas Gov. John Connally are brought to Parkland after being shot in a motorcade in downtown Dallas.


The School of Allied Health Sciences, now known as the School of Health Professions, is established at UT Southwestern.


Dr. Charles Sprague is made the first President of UT Southwestern.


Dr. Ronald Estabrook becomes the first Dean of the Graduate School of Biomedical Sciences.


The Davis quintuplets are delivered at Parkland Memorial Hospital by UT Southwestern faculty, the first quintuplets to survive in Texas.


In the New England Journal of Medicine, Drs. Roger Unger and Philip Raskin present evidence that the hormone glucagon has a significant role in human diabetes.


Dr. Ronald W. Estabrook is the first UT Southwestern faculty member elected to the National Academy of Sciences.


James W. Aston Ambulatory Care Center opens its doors to receive its first patient.


Drs. Michael Brown and Joseph Goldstein win the Nobel Prize in Physiology or Medicine for their discoveries concerning the regulation of cholesterol metabolism.


The Howard Hughes Medical Institute selects UT Southwestern as the site of one of its largest research centers.


UT Southwestern names Dr. Kern Wildenthal its second President in the Medical Center’s history.


The Ida M. Green Award is established to recognize an outstanding female graduate student.


Dr. Johann Deisenhofer receives the Nobel Prize in Chemistry for using X-ray crystallography to describe the structure of a protein involved in photosynthesis.

Dr. Johann Deisenhofer


Dr. Scott Grundy reports that the Mediterranean diet, rich in monounsaturated fat – the type found in olive oil – is superior to a low-fat diet.


Doors open at the Mary Nell and Ralph B. Rogers Magnetic Resonance Center, the first building on the North Campus.



Dr. Ellen Vitetta becomes the first female scientist from UT Southwestern elected to the National Academy of Sciences.


Dr. Alfred Gilman accepts the Nobel Prize in Physiology or Medicine for the discovery of G proteins.

Dr. Alfred Gilman


The Dallas Heart Study, a groundbreaking investigation of cardiovascular disease involving thousands of Dallas County residents, is launched.


The Innovations in Medicine campaign launches and eventually raises more than $750 million, funding advancements in the understanding and treatment of diseases where major breakthroughs appear to be feasible in the foreseeable future.


Dr. Linda Buck, a 1980 alumna of the Graduate School, receives the Nobel Prize in Physiology or Medicine for her work to understand the sense of smell.

Dr. Linda Buck


By taking over operating responsibilities for St. Paul and Zale Lipshy University Hospitals, UT Southwestern lays the foundation for a University Health System.


UT Southwestern introduces the electronic medical record portal “MyChart,” capping an effort that began in 2002 as the Institution becomes the first health care facility in North Texas to switch to electronic medical records.


The School of Health Professions becomes the first UT System institution to offer a doctorate program in physical therapy.


Dr. Daniel K. Podolsky becomes the third President of UT Southwestern.

Daniel K. Podolsky


Former Texas Gov. William P. Clements Jr. makes an unprecedented $100 million gift to Southwestern Medical Foundation.

William P. Clements


UT Southwestern dedicates the BioCenter, a springboard to drive biomedical innovation in North Texas and encourage the commercialization of University-created technologies.



The Office of Global Health is established, and a scientific partnership begins with Sun Yat-sen University and its First Affiliated Hospital in Guangzhou, China.


Dr. Bruce Beutler receives the Nobel Prize in Physiology or Medicine for discovering receptor proteins that recognize disease-causing agents and activate innate immunity – the first step in the body’s immune response.


UT Southwestern confers its 10,000th medical degree during Commencement, a remarkable achievement for an institution that awarded its first degrees in 1944.


The first UT Southwestern Clinical Center opens in Richardson/Plano.

Richardson Clinic


Planning to develop a new Medical School curriculum begins. Two years later, the Class of 2019 begins instruction under the new three-phase curriculum.


Dr. Thomas Südhof receives the Nobel Prize in Physiology or Medicine for discovering key information about how cellular transport systems work.


The UT Southwestern Moncrief Cancer Institute opens in Fort Worth.

Moncrief Cancer Institute


William P. Clements Jr. University Hospital opens. Every aspect is designed to enhance the patient’s care and experience and to reflect the integration of UT Southwestern’s missions of research, education, and clinical care.

William P. Clements University Hospital


The Medical Center builds for the future by establishing the Peter O’Donnell Jr. Brain Institute and the Lyda Hill Department of Bioinformatics.


The National Cancer Institute designates the Harold C. Simmons Cancer Center as a Comprehensive Cancer Center.

Harold C. Simmons Cancer Center


Dr. Helen Hobbs receives the international Breakthrough Prize in Life Sciences for discoveries showing how certain genes predispose people to heart attacks and other genes offer protection from heart disease.

Dr. Helen Hobbs


The newly opened cryo-electron microscope facility features a unique collection of instruments that researchers can use to view 3-D images of objects as tiny as an atom.


UT Southwestern and Texas Health Resources form Southwestern Health Resources, a clinically integrated health care network.


UT Southwestern breaks ground on a 650,000-square-foot expansion of Clements University Hospital, capping 75 years of the Medical Center’s existence while signaling its commitment to delivering the future of medicine for generations to come.